MHC Class I Polypeptide Related Sequence A (MICA) Antibody
312€ (60 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
MHC Class I Polypeptide Related Sequence A (MICA) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx001216
Tested Applications
WB
Description
MICA Antibody is a Rabbit Polyclonal antibody against MICA. MICA and MICB are stress-induced antigens that are related to major histocompatibility complex (MHC) class I molecules. MICA and MICB are frequently expressed in epithelial tumors. These highly glycosylated cell surface proteins are stably expressed without conventional class I peptide ligands or association with b-2-Microglobulin. The expression is induced on proliferating or heat shock-stressed epithelial cells. MICA and MICB are broadly recognized by intestinal epithelial Vd1 gd T cells expressing variable TCRs, suggesting that these antigens may play a central role in the signaling of cellular distress to evoke immune responses in the intestinal epithelium.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: MHC Class I Polypeptide Related Sequence A (MICA) Immunogen: Recombinant fusion protein corresponding to human MICA |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 31 kDa/42 kDa Observed MW: 43 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q29983 |
| Gene ID | 4276 |
| NCBI Accession | NP_000238.1 |
| Background | Antibody anti-MICA |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Productos relacionados
MHC Class I Polypeptide Related Sequence A (MICA) Antibody
MICA Antibody is a Rabbit Polyclonal antibody against MICA. MICA and MICB are stress-induced antigens that are related …
Ver producto
MHC Class I Polypeptide Related Sequence A (MICA) Antibody
MICA is the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surfa…
Ver producto
Human MHC Class I Polypeptide Related Sequence A (MICA) ELISA Kit
Human MHC Class I Polypeptide Related Sequence A (MICA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurem…
Ver producto