Microfibril Associated Protein 3 Like (MFAP3L) Antibody (Biotin)

Este producto es parte de MFAP - microfibril associated protein
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169€ (20 µg)

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935106861
info@markelab.com
name
Microfibril Associated Protein 3 Like (MFAP3L) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx304485
tested applications
ELISA

Description

MFAP3L Antibody (Biotin) is a Rabbit Polyclonal against MFAP3L conjugated to Biotin.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetMicrofibril Associated Protein 3 Like (MFAP3L)
HostRabbit
ReactivityHuman
Recommended DilutionOptimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationBiotin
IsotypeIgG
Purity> 95%
PurificationPurified by Protein G.
Size 120 µg
Size 250 µg
Size 3100 µg
Size 4200 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA
Buffer0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDO75121
Gene ID9848
NCBI AccessionNP_001009554.1, NM_001009554.3, NP_001288576.1, NM_001301647.1, NP_001288577.1, NM_001301648.1, NP_067679.6, NM_021647.7
OMIM616523
AliasNYD-sp9,Testis development protein NYD-SP9
BackgroundAntibody anti-MFAP3L
StatusRUO

Descripción

Microfibril-Associated Protein 3-Like (MFAP3L) is a protein structurally related to MFAP3, sharing homology in domains involved in microfibril assembly and extracellular matrix (ECM) interactions. However, MFAP3L appears to have distinct expression patterns and biological functions. It is predominantly expressed in tissues with significant mechanical demands, such as the vasculature, lung, and connective tissues, suggesting a role in maintaining tissue elasticity and structural stability. MFAP3L contains conserved cysteine-rich domains, which allow it to form stable interactions with ECM proteins like fibrillin and elastin. These interactions are crucial for the proper assembly and stabilization of microfibrils, which are key components of elastic fibers. MFAP3L may also regulate the biomechanical properties of tissues, contributing to their strength and elasticity under mechanical stress. MFAP3L is implicated in microfibril development and maintenance of elastic fibers. It likely supports the organization of fibrillin-rich microfibrils, facilitating their role in tissue resilience.
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