Methyl-CpG Binding Domain Protein 3 (MBD3) Antibody
52€ (10 µg)
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935106861
info@markelab.com
name
Methyl-CpG Binding Domain Protein 3 (MBD3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx013349
tested applications
ELISA, WB
Description
Rabbit polyclonal antibody against MBD3 protein. Immunogen region is C-terminal.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Methyl-CpG Binding Domain Protein 3 (MBD3) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95983 |
| Background | Antibody anti-MBD3 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
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