MBD3 antibody
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935106861
info@markelab.com
name
MBD3 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05035
tested applications
ELISA, WB, IHC, IF, IP
Description
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | methyl-CpG binding domain protein 3 (MBD3) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 33 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC, IF, IP |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | O95983 |
| Gene ID | 53615 |
| Alias | Methyl-CpG-binding domain protein 3,Methyl-CpG-binding protein MBD3,MBD3 |
| Background | Antibody anti-MBD3 |
| Status | RUO |
| Note | Mol. Weight 33 kDa |
Descripción
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MBD3 antibody
Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself(PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides(in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides(PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases.
Ver Producto