Meteorin Like Protein (METRNL) Antibody (FITC)
Pida mas información
935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-METRNL
proveedor
Abbexareference
abx107077Tested Applications
reactivity
Humanstatus
RUOclonality
PolyclonalDescripción
Meteorin-like protein Antibody (FITC) is a Rabbit Polyclonal antibody against Meteorin-like protein conjugated to FITC.
Background
Meteorin-like protein (METRNL) shares structural similarity with Meteorin and is secreted primarily by adipose tissue and muscle, where it plays a role in energy metabolism and inflammation. METRNL has been identified as a myokine and adipokine that promotes thermogenesis in beige adipocytes by inducing the expression of uncoupling protein 1 (UCP1) and activating macrophages to secrete IL-4 and IL-13. This process enhances energy expenditure and improves metabolic health, making METRNL a potential therapeutic target for obesity and metabolic syndrome. Additionally, METRNL exhibits anti-inflammatory properties, modulating immune responses in adipose tissue and skeletal muscle during exercise or metabolic stress. Recent research indicates its involvement in tissue repair and regeneration, particularly in response to injury or disease, through its interaction with signaling pathways like AMPK and MAPK.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Meteorin Like Protein (METRNL)
host
Rabbit
conjugation
FITC
form
Liquid
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
METRNL
dry ice
No
availability
Shipped within 5-10 working days.
alias
Subfatin
uniprot id
NCBI accession
NP_001004431.1, NM_001004431.2
note
This product is for research use only.
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