Meteorin-like protein (METRNL) Antibody
299€ (50 µl)
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935106861
info@markelab.com
name
Meteorin-like protein (METRNL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx341117
tested applications
ELISA, IHC, FCM
Description
Meteorin-like protein (METRNL) Antibody is a Mouse Monoclonal antibody for the detection of Human MERTNL.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Meteorin-like protein (METRNL) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Purity | > 95% |
| Purification | Purified by Protein A chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC, FCM |
| Buffer | PBS, pH 7.3, containing 0.1% Sodium Azide, 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q641Q3 |
| Alias | Subfatin |
| Background | Antibody anti-METRNL |
| Status | RUO |
Descripción
Meteorin-like protein (METRNL) shares structural similarity with Meteorin and is secreted primarily by adipose tissue and muscle, where it plays a role in energy metabolism and inflammation. METRNL has been identified as a myokine and adipokine that promotes thermogenesis in beige adipocytes by inducing the expression of uncoupling protein 1 (UCP1) and activating macrophages to secrete IL-4 and IL-13. This process enhances energy expenditure and improves metabolic health, making METRNL a potential therapeutic target for obesity and metabolic syndrome. Additionally, METRNL exhibits anti-inflammatory properties, modulating immune responses in adipose tissue and skeletal muscle during exercise or metabolic stress. Recent research indicates its involvement in tissue repair and regeneration, particularly in response to injury or disease, through its interaction with signaling pathways like AMPK and MAPK.
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