Meteorin Like Protein (METRNL) Antibody
169€ (20 µg)
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935106861
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name
Meteorin Like Protein (METRNL) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx109325
tested applications
ELISA, WB
Description
Meteorin-like protein Antibody is a Rabbit Polyclonal antibody against Meteorin-like protein.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Meteorin Like Protein (METRNL) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, containing 0.5% BSA, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q641Q3 |
| Gene ID | 284207 |
| NCBI Accession | NP_001004431.1, NM_001004431.2 |
| OMIM | 616241 |
| Alias | Subfatin |
| Background | Antibody anti-METRNL |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Meteorin-like protein (METRNL) shares structural similarity with Meteorin and is secreted primarily by adipose tissue and muscle, where it plays a role in energy metabolism and inflammation. METRNL has been identified as a myokine and adipokine that promotes thermogenesis in beige adipocytes by inducing the expression of uncoupling protein 1 (UCP1) and activating macrophages to secrete IL-4 and IL-13. This process enhances energy expenditure and improves metabolic health, making METRNL a potential therapeutic target for obesity and metabolic syndrome. Additionally, METRNL exhibits anti-inflammatory properties, modulating immune responses in adipose tissue and skeletal muscle during exercise or metabolic stress. Recent research indicates its involvement in tissue repair and regeneration, particularly in response to injury or disease, through its interaction with signaling pathways like AMPK and MAPK.
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