Metalloproteinase Inhibitor 1 (TIMP1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Metalloproteinase inhibitor 1 Antibody is a Rabbit Primary antibodies antibody against Metalloproteinase inhibitor 1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Metalloproteinase Inhibitor 1 (TIMP1) |
| Host | Rabbit |
| Reactivity | Rat |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P30120 |
| Gene ID | 116510 |
| Alias | Tissue inhibitor of metalloproteinases 1,EPA,EPO,HCI,CLGI,TIMP,TIMP-1 |
| Background | Antibody anti-TIMP1 |
| Status | RUO |
TIMP1 is a member of the TIMP family and acts as a natural inhibitor of matrix metalloproteinases (MMPs), which are enzymes that degrade components of the extracellular matrix TIMP1 regulates tissue remodeling, inflammation, and wound healing by inhibiting MMP activity and preventing excessive matrix breakdown It also exhibits anti-apoptotic properties by binding to cell surface receptors and activating survival pathways TIMP1 plays a role in cancer progression where its overexpression can inhibit tumor invasion and metastasis by limiting MMP activity, while paradoxically, it can also promote tumor growth by stimulating cell proliferation and angiogenesis Dysregulation of TIMP1 is observed in diseases such as fibrosis, cardiovascular disease, and chronic inflammatory conditions, where altered MMP activity contributes to tissue damage and remodeling TIMP1’s dual role as a regulator of extracellular matrix turnover and cell signaling makes it a key player in both normal physiological processes and pathological conditions
Related Products
Metalloproteinase Inhibitor 1 (TIMP1) Antibody
TIMP1 belongs to the TIMP family. The proteins in this family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function.
Ver Producto
Metalloproteinase Inhibitor 1 (TIMP1) Antibody
Timp Metallopeptidase Inhibitor 1 Antibody is a Rabbit Polyclonal antibody against Timp Metallopeptidase Inhibitor 1.
Ver Producto
Human Metalloproteinase Inhibitor 1 (TIMP1) ELISA Kit
Human Metalloproteinase Inhibitor 1 (TIMP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Metalloproteinase Inhibitor 1 (TIMP1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Tissue Inhibitors Of Metalloproteinase 1 (TIMP1)
Ver Producto