Metalloendopeptidase OMA1, Mitochondrial (OMA1) Antibody (HRP)
169€ (20 µg)
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935106861
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name
Metalloendopeptidase OMA1, Mitochondrial (OMA1) Antibody (HRP)
category
Primary Antibodies
provider
Abbexa
reference
abx310442
tested applications
ELISA
Description
OMA1 Antibody (HRP) is a Rabbit Polyclonal against OMA1 conjugated to HRP.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Metalloendopeptidase OMA1, Mitochondrial (OMA1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96E52 |
| Gene ID | 115209 |
| NCBI Accession | NP_660286.1, NM_145243.4 |
| OMIM | 61781 |
| Background | Antibody anti-OMA1 |
| Status | RUO |
Descripción
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OMA1 antibody
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
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