OMA1 antibody
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935106861
info@markelab.com
name
OMA1 antibody
category
Primary Antibodies
provider
FineTest
reference
FNab05991
tested applications
ELISA, WB
Description
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | OMA1 homolog, zinc metallopeptidase (OMA1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:500-1:2000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 60 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q96E52 |
| Gene ID | 115209 |
| Alias | Metalloendopeptidase OMA1, mitochondrial,Metalloprotease-related protein 1 (MPRP-1),Overlapping with the m-AAA protease 1 homolog,OMA1,MPRP1 |
| Background | Antibody anti-OMA1 |
| Status | RUO |
| Note | Mol. Weight 60 kDa |
Descripción
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Human OMA1 (Metalloendopeptidase OMA1, mitochondrial) ELISA Kit
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OMA1 antibody
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
Ver Producto