Membrane Primary Amine Oxidase (AOC3) Antibody
195€ (20 µl)
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name
Membrane Primary Amine Oxidase (AOC3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001627
tested applications
ELISA, WB
Description
AOC3 Antibody is a Rabbit Polyclonal antibody against AOC3. This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Membrane Primary Amine Oxidase (AOC3) Immunogen: Recombinant protein corresponding to AOC3. The exact sequence is proprietary. |
| Host | Rabbit |
| Reactivity | Mouse, Rat |
| Assay Type | Concentration: > 0.2 mg/ml |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 85 kDa Observed MW: 101 kDa |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q16853 |
| Gene ID | 8639 |
| NCBI Accession | NP_003725.1 |
| Alias | AOC3,VAP1,HPAO |
| Background | Antibody anti-AOC3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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AOC3 antibody
AOC3(membrane primary amine oxidase) is also name as copper amine oxidase, HPAO, SSAO, VAP1 and belongs to the copper/topaquinone oxidase family. It is expressed on the surface of endothelial cells and is involved in leukocyte trafficking between blood and tissues under physiologic and pathologic conditions(PMID:17947691). AOC3 is highly expressed in adipocytes and smooth muscle cells and it can be N-and O-glycosylated(PMID:16046623). This protein can exsit as a homodimer(PMID:8625974).
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