Membrane-Bound Transcription Factor Site-1 Protease (MBTPS1) Antibody
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Description
MBTPS1 Antibody is a Rabbit Polyclonal antibody against MBTPS1. This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Membrane-Bound Transcription Factor Site-1 Protease (MBTPS1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q14703 |
| Gene ID | 8720 |
| NCBI Accession | NP_003782.1 |
| OMIM | 603355 |
| Background | Antibody anti-MBTPS1 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
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Membrane-Bound Transcription Factor Site-1 Protease (MBTPS1) Antibody
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