Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) Antibody
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Description
Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCHF4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P2E8 |
| Background | Antibody anti-MARCHF4 |
| Status | RUO |
Descripción
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Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) Antibody
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Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) Antibody
Membrane Associated Ring-CH-Type Finger 4 (MARCHF4) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCHF4 reduces surface accumulation of several membrane glycoproteins by directing them to the endosomal compartment (Bartee et al., 2004 [PubMed 14722266]).
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