Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) Antibody
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Description
MARCH-I Antibody is a Goat Polyclonal antibody against MARCH-I.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) |
| Host | Goat |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 55016, 72925, 361135 |
| NCBI Accession | NP_060393.1 |
| Background | Antibody anti-MARCHF1 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
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Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) Antibody
MARCHF1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCHF1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).
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MARCH1 Antibody is a Rabbit Polyclonal against MARCH1.
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MARCH1 Antibody is a Rabbit Polyclonal against MARCH1.
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