Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) Antibody
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Description
MARCH1 Antibody is a Rabbit Polyclonal against MARCH1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/40000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8TCQ1 |
| Gene ID | 55016 |
| Background | Antibody anti-MARCHF1 |
| Status | RUO |
Descripción
Related Products
Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) Antibody
MARCHF1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCHF1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).
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Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) Antibody
MARCH1 Antibody is a Rabbit Polyclonal against MARCH1.
Ver Producto
Membrane Associated Ring-CH-Type Finger 1 (MARCHF1) Antibody
MARCH1 Antibody is a Rabbit Polyclonal against MARCH1.
Ver Producto