Melanoma Cell Adhesion Molecule (CD146) Antibody (PerCP)

Este producto es parte de MCAM - melanoma cell adhesion molecule
Product Graph
429€ (100 tests)

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935106861
info@markelab.com
name
Melanoma Cell Adhesion Molecule (CD146) Antibody (PerCP)
category
Primary Antibodies
provider
Abbexa
reference
abx140614
tested applications
FCM

Description

Melanoma Cell Adhesion Molecule (CD146) Antibody is a Mouse Monoclonal against Melanoma Cell Adhesion Molecule (CD146).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Melanoma Cell Adhesion Molecule (CD146)
Host
Mouse
Reactivity
Human, Mouse, Rabbit, Dog
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
PerCP
Isotype
IgG1
Clone ID
O278
Size 1
100 tests
Tested Applications
FCM
Buffer
Stabilizing PBS solution containing 15 mM sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
P43121
Gene ID
4162
Alias
Cell surface glycoprotein MUC18,CD146,MUC18,HEMCAM,METCAM,MelCAM,Cell surface glycoprotein P1H12,Melanoma-associated antigen A32,S-endo 1 endothelial-associated antigen
Background
Antibody anti-MCAM
Status
RUO

Descripción

The melanoma cell adhesion molecule (MCAM), also known as CD146 or MUC18, is a transmembrane glycoprotein belonging to the immunoglobulin superfamily (IgSF). MCAM was initially identified as an adhesion molecule highly expressed in melanoma cells, and since then, it has been shown to play a role in various cellular processes beyond melanoma, including angiogenesis, inflammation, and immune cell trafficking. MCAM is expressed in a variety of cell types, such as endothelial cells, smooth muscle cells, and immune cells, contributing to its diverse biological functions. Its key role in cellular adhesion makes it critical in both normal physiological processes like vascular integrity and in pathological conditions such as cancer metastasis, cardiovascular disease, and inflammation.

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