Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody
292.5€ (80 µl)
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Name
Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx032957
Tested Applications
ELISA, WB, IHC, FCM
Description
MAPE is an antigen that is predominantly expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. This expression pattern is similar to that of other CT antigens, such as MAGE, BAGE and GAGE. However, unlike these other CT antigens, its gene is also expressed in acute leukemias.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Melanoma Antigen Preferentially Expressed In Tumors (PRAME) Immunogen: KLH-conjugated synthetic peptide between 476-502 amino acids from the C-terminal region of human MAPE. |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/2000, IHC-P: 1/50 - 1/100, FCM: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | Calculated MW: 57.9 kDa |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78395 |
| Gene ID | 23532 |
| NCBI Accession | NP_006106.1, NP_996836.1, NP_996837.1, NP_996838.1, NP_996839.1 |
| OMIM | 606021 |
| Background | Antibody anti-PRAME |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
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