Melanocortin 3 Receptor (MC3R) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Melanocortin 3 Receptor (MC3R) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx336468
Tested Applications
ELISA
Description
MC3R Antibody (HRP) is a Rabbit Polyclonal against MC3R.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Melanocortin 3 Receptor (MC3R) Immunogen: Recombinant Human Melanocortin receptor 3 protein (38-74AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P41968 |
| Gene ID | 4159 |
| Alias | MC3R,BMIQ9,MC3,MC3-R,OB20,OQTL,γ-MSH receptor,melanocortin receptor 3 |
| Background | Antibody anti-MC3R |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
MC3R is a G protein-coupled receptor activated by melanocortins, including α-MSH, β-MSH, and ACTH. MC3R is expressed primarily in the hypothalamus, pituitary gland, and other peripheral tissues, where it plays a critical role in energy homeostasis, feeding behavior, and circadian rhythms. MC3R signaling involves coupling to Gs proteins, leading to increased cAMP levels and activation of downstream pathways that regulate appetite suppression and energy expenditure. In the hypothalamus, MC3R modulates the activity of neuropeptides, such as AgRP and POMC, balancing food intake and energy utilization. Dysregulation of MC3R has been linked to obesity, metabolic syndrome, and circadian rhythm disorders. MC3R also contributes to immune regulation, influencing anti-inflammatory responses and macrophage function. Emerging evidence highlights its role in skeletal muscle metabolism and cardiovascular function. Therapeutic targeting of MC3R is being explored for obesity treatment, metabolic disorders, and inflammatory conditions, emphasizing its importance in energy balance and homeostatic regulation.
Productos relacionados
Melanocortin 3 Receptor (MC3R) Antibody
MC3R is a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expresse…
Ver producto
Melanocortin 3 Receptor (MC3R) Antibody
MC3R Antibody is a Rabbit Polyclonal against MC3R.…
Ver producto
Melanocortin 3 Receptor (MC3R) Antibody
MC3R Antibody is a Rabbit Polyclonal against MC3R.…
Ver producto