Meiotic recombination protein SPO11 (SPO11) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Meiotic recombination protein SPO11 (SPO11) Antibody is a Rabbit Polyclonal antibody for the detection of Human SPO11.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Meiotic recombination protein SPO11 (SPO11) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G chromatography. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y5K1 |
| Gene ID | 23626 |
| OMIM | 605114 |
| Background | Antibody anti-SPO11 |
| Status | RUO |
Descripción
Related Products
SPO11 antibody
Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Ver Producto
SPO11, Initiator of Meiotic Double Stranded Breaks (SPO11) Antibody
Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.
Ver Producto
SPO11, Initiator of Meiotic Double Stranded Breaks (SPO11) Antibody
SPO11 Antibody is a Rabbit Polyclonal against SPO11.
Ver Producto