Meiotic Recombination Protein REC8 Homolog (REC8) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Meiotic Recombination Protein REC8 Homolog (REC8) Antibody is a Rabbit Polyclonal against Meiotic Recombination Protein REC8 Homolog (REC8). This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Meiotic Recombination Protein REC8 Homolog (REC8) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/3000, ELISA: 1/5000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. |
| Size 1 | 10 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 300 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O95072 |
| Gene ID | 9985 |
| NCBI Accession | NP_001041670.1, NM_001048205.1 |
| OMIM | 608193 |
| Background | Antibody anti-REC8 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
Related Products
REC8 antibody
Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II(By similarity).
Ver Producto
Recombinant Human REC8
Ver Producto
Meiotic Recombination Protein REC8 Homolog (REC8) Antibody
Meiotic Recombination Protein REC8 Homolog (REC8) Antibody is a Rabbit Polyclonal against Meiotic Recombination Protein REC8 Homolog (REC8). This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Ver Producto