Matrix Remodelling Associated Protein 5 (MXRA5) Antibody

Este producto es parte de MXRA - matrix remodeling associated
Product Graph
299€ (100 µl)

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935106861
info@markelab.com
name
Matrix Remodelling Associated Protein 5 (MXRA5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx130610
tested applications
WB, IHC, IF/ICC

Description

MXRA5 Antibody is a Rabbit Polyclonal against MXRA5.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Matrix Remodelling Associated Protein 5 (MXRA5)
Host
Rabbit
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Purification
Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Size 1
100 µl
Size 2
200 µl
Size 3
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Shipped within 5-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q9NR99
Alias
Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan,Adlican
Background
Antibody anti-MXRA5
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

Matrix Remodeling Associated 5 (MXRA5) is a glycoprotein involved in extracellular matrix (ECM) organization and tissue remodeling. It plays a significant role in maintaining ECM integrity, regulating cell adhesion, and modulating cellular responses during tissue repair and remodeling. MXRA5 expression is associated with processes such as wound healing, fibrosis, and inflammation, where ECM dynamics are critical. Dysregulation of MXRA5 has been linked to fibrotic diseases and cancer, particularly in the tumor microenvironment, where it promotes cell migration, invasion, and metastasis by altering ECM composition and structure. Studies suggest that MXRA5 may also influence immune responses by modulating cytokine signaling pathways. Its potential as a biomarker for certain cancers and fibrotic conditions is under investigation, and it represents a promising therapeutic target for diseases associated with abnormal ECM remodeling. Further research is required to fully understand its molecular mechanisms and functional significance in health and disease.

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