Human Matrix Remodelling Associated Protein 5 (MXRA5) Protein
234€ (10 µg)
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935106861
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name
Human Matrix Remodelling Associated Protein 5 (MXRA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx650820
tested applications
WB, SDS-PAGE
Description
Human MXRA5 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Matrix Remodelling Associated Protein 5 (MXRA5) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 34.9 kDa Observed MW (SDS-PAGE): 35 kDa Concentration: Prior to lyophilization: 150 µg/ml Sequence Fragment: Pro2542-Phe2828 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NR99 |
| Alias | Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan,Adlican |
| Background | Protein MXRA5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Matrix Remodeling Associated 5 (MXRA5) is a glycoprotein involved in extracellular matrix (ECM) organization and tissue remodeling. It plays a significant role in maintaining ECM integrity, regulating cell adhesion, and modulating cellular responses during tissue repair and remodeling. MXRA5 expression is associated with processes such as wound healing, fibrosis, and inflammation, where ECM dynamics are critical. Dysregulation of MXRA5 has been linked to fibrotic diseases and cancer, particularly in the tumor microenvironment, where it promotes cell migration, invasion, and metastasis by altering ECM composition and structure. Studies suggest that MXRA5 may also influence immune responses by modulating cytokine signaling pathways. Its potential as a biomarker for certain cancers and fibrotic conditions is under investigation, and it represents a promising therapeutic target for diseases associated with abnormal ECM remodeling. Further research is required to fully understand its molecular mechanisms and functional significance in health and disease.
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