Marginal Zone B- And B1-Cell-Specific Protein (MZB1) Antibody
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Description
MZB1 Antibody is a Rabbit Polyclonal against MZB1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Marginal Zone B- And B1-Cell-Specific Protein (MZB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000 - 1/20000, IHC: 1/50 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8WU39 |
| Gene ID | 51237 |
| OMIM | 609447 |
| Background | Antibody anti-MZB1 |
| Status | RUO |
Descripción
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Human MZB1 (Marginal zone B-and B1-cell-specific protein) ELISA Kit
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MZB1 antibody
Associates with immunoglobulin M(IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity(By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
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