MZB1 antibody
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Description
Associates with immunoglobulin M(IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity(By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | hypothetical protein MGC29506 (MZB1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1:500-1:2000; IHC: 1:20-1:200 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 21 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB, IHC |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | Q8WU39 |
| Gene ID | 51237 |
| Alias | Marginal zone B- and B1-cell-specific protein,Mesenteric estrogen-dependent adipose 7 (MEDA-7),Plasma cell-induced resident endoplasmic reticulum protein (Plasma cell-induced resident ER protein, pERp1),Proapoptotic caspase adapter protein,MZB1,MEDA7,PACAP |
| Background | Antibody anti-MZB1 |
| Status | RUO |
| Note | Mol. Weight 21 kDa |
Descripción
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Human MZB1 (Marginal zone B-and B1-cell-specific protein) ELISA Kit
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MZB1 antibody
Associates with immunoglobulin M(IgM) heavy and light chains and promotes IgM assembly and secretion. May exert its effect by acting as a molecular chaperone or as an oxidoreductase as it displays a low level of oxidoreductase activity(By similarity). Isoform 2 may be involved in regulation of apoptosis. Helps to diversify peripheral B-cell functions by regulating Ca(2+) stores, antibody secretion and integrin activation. Acts as a hormone-regulated adipokine/proinflammatory cytokine that is implicated in causing chronic inflammation, affecting cellular expansion and blunting insulin response in adipocytes. May have a role in the onset of insulin resistance.
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