Microtubule-Associated Protein Tau Phospho-Ser404 (MAPT pS404) Antibody

Microtubule-Associated Protein Tau Phospho-Ser404 (MAPT pS404) Antibody
208€ (20 µl)

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Name
Microtubule-Associated Protein Tau Phospho-Ser404 (MAPT pS404) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx000222
Tested Applications
ELISA, WB, IHC, IF/ICC

Description

MAPT (pS404) Antibody is a Rabbit Polyclonal antibody against MAPT (pS404). This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.

Documentos del producto

Instrucciones
Data sheet
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Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Microtubule-Associated Protein Tau Phospho-Ser404 (MAPT pS404)
Immunogen: Synthetic peptide corresponding to MAPT pS404. The exact sequence is proprietary.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Assay Type
Concentration: > 0.2 mg/ml
Recommended Dilution
ELISA: 1 µg/ml, WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Observed MW
Calculated MW: 79 kDa  Observed MW: 65 kDa
Purification
Purified by affinity chromatography.
Size 1
20 µl
Size 2
100 µl
Size 3
2 × 100 µl
Form
Liquid
Tested Applications
ELISA, WB, IHC, IF/ICC
Buffer
PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P10636
Gene ID
4137
NCBI Accession
NP_005901.2
OMIM
157140
Background
Antibody anti-MAPT
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

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