MAP Kinase-Activated Protein Kinase 5 Phospho-Ser93 (MAPKAPK5 pS93) Antibody
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Description
The protein encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | MAP Kinase-Activated Protein Kinase 5 Phospho-Ser93 (MAPKAPK5 pS93) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Assay Data | Modification: Phosphorylation // Target Modification: Ser93 |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by protein G affinity chromatography. Then, the antibody fraction was peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody was eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q8IW41 |
| NCBI Accession | NP_003659.2, NP_620777.1 |
| Background | Antibody anti-MAPKAPK5 |
| Status | RUO |
Descripción
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