Major Histocompatibility Complex, Class II, DR Beta 3 (HLA-DRB3) Antibody (HRP)
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Description
HLA-DRB3 Antibody (HRP) is a Rabbit Polyclonal against HLA-DRB3.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Major Histocompatibility Complex, Class II, DR Beta 3 (HLA-DRB3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P79483 |
| Gene ID | 3125 |
| Background | Antibody anti-HLA-DRB3 |
| Status | RUO |
Descripción
Related Products
Major Histocompatibility Complex, Class II, DR Beta 3 (HLA-DRB3) Antibody
HLA-DRB3 Antibody is a Rabbit Polyclonal antibody against HLA-DRB3. HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. DRB1 is expressed at a level five times higher than its paralogues DRB3, DRB4 and DRB5. The presence of DRB3 is linked with allelic variants of DRB1, otherwise it is omitted. There are 4 related pseudogenes: DRB2, DRB6, DRB7, DRB8 and DRB9. [provided by RefSeq, Jul 2008].
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Major Histocompatibility Complex, Class II, DR Beta 3 (HLA-DRB3) Antibody
HLA-DRB3 Antibody is a Rabbit Polyclonal antibody against HLA-DRB3.
Ver ProductoMajor Histocompatibility Complex, Class II, DR Beta 3 (HLA-DRB3) Antibody (HRP)
HLA-DRB3 Antibody (HRP) is a Rabbit Polyclonal against HLA-DRB3.
Ver Producto