Macrophage Scavenger Receptor Types I And II (MSR1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Macrophage Scavenger Receptor Types I And II (MSR1) Antibody is a Mouse Monoclonal antibody for the detection of Macrophage Scavenger Receptor Types I And II (MSR1) in Human samples.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Macrophage Scavenger Receptor Types I And II (MSR1) |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1 mg/ml |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | G502 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4°C if the entire vial will be used within 1 week. Aliquot and store at -20°C or -80°C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21757 |
| Gene ID | 4481 |
| NCBI Accession | NP_002436.1 |
| Alias | Macrophage scavenger receptor types I and II,SRA,SR-A,CD204,SR-AI,phSR1,phSR2,SCARA1,SR-AII,SR-AIII,Macrophage acetylated LDL receptor I and II,Scavenger receptor class A member 1 |
| Background | Antibody anti-MSR1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
Related Products
Human MSR1 (Macrophage Scavenger Receptor 1) ELISA Kit
Ver Producto
Human MSR1 (Macrophage Scavenger Receptor 1) QuickTest ELISA Kit
Ver Producto
Macrophage Scavenger Receptor 1 (MSR1) Antibody
MSR1 Antibody is a Rabbit Polyclonal antibody against MSR1. This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008].
Ver Producto