Human MSR1 (Macrophage Scavenger Receptor 1) QuickTest ELISA Kit
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Product specifications
| Category | ELISA Kits |
| Reactivity | Human |
| Assay Data | 120 minutes |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, cell culture supernatant, cell lysate or tissue lysate, other biological fluid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P21757 |
| Alias | Macrophage scavenger receptor types I and II,SRA,SR-A,CD204,SR-AI,phSR1,phSR2,SCARA1,SR-AII,SR-AIII,Macrophage acetylated LDL receptor I and II,Scavenger receptor class A member 1 |
| Background | Elisa kits for MSR1 |
| Status | RUO |
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Macrophage Scavenger Receptor 1 (MSR1) Antibody
MSR1 Antibody is a Rabbit Polyclonal antibody against MSR1. This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008].
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