Macrophage Scavenger Receptor 1 (MSR1) Antibody (Biotin)

Este producto es parte de MSR1 - macrophage scavenger receptor 1
Product Graph
182€ (25 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Macrophage Scavenger Receptor 1 (MSR1) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx412949
tested applications
FCM

Description

Macrophage Scavenger Receptor Types I And II (CD204) Antibody (Biotin) is a Rat Monoclonal antibody against Macrophage Scavenger Receptor Types I And II (CD204).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Macrophage Scavenger Receptor 1 (MSR1)
Host
Rat
Reactivity
Mouse
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Biotin
Isotype
IgG2b
Purification
Purified
Size 1
25 µg
Size 2
100 µg
Form
Liquid
Tested Applications
FCM
Buffer
PBS, 1% BSA. Contains sodium azide.
Availability
Shipped within 3-7 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P30204
Alias
Macrophage scavenger receptor types I and II,SRA,SR-A,CD204,SR-AI,phSR1,phSR2,SCARA1,SR-AII,SR-AIII,Macrophage acetylated LDL receptor I and II,Scavenger receptor class A member 1
Background
Antibody anti-MSR1
Status
RUO
Note
Concentration: 0.1 mg/ml - 

Descripción

Macrophage Scavenger Receptor 1 (MSR1), also known as CD204, is a multifunctional receptor primarily expressed on macrophages and other cells of the mononuclear phagocyte system. MSR1 is a critical player in the immune system, where it recognizes and binds to various ligands, including modified lipoproteins, pathogens, and apoptotic cells, thereby aiding in host defense, tissue homeostasis, and inflammation. MSR1 functions by clearing endogenous and exogenous substances from the bloodstream and tissues, including oxidized low-density lipoproteins (oxLDL), a process essential in preventing atherosclerosis and other inflammatory diseases. Due to its role in these processes, MSR1 has been studied extensively in the context of immune responses, pathogen recognition, and chronic inflammatory conditions, including cardiovascular diseases and cancer.

Related Products

EH3386

Human MSR1 (Macrophage Scavenger Receptor 1) ELISA Kit

Ver Producto
QT-EH3386

Human MSR1 (Macrophage Scavenger Receptor 1) QuickTest ELISA Kit

Ver Producto
abx001570

Macrophage Scavenger Receptor 1 (MSR1) Antibody

MSR1 Antibody is a Rabbit Polyclonal antibody against MSR1. This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages. [provided by RefSeq, Jul 2008].

Ver Producto