Lysosomal Associated Membrane Protein 3 (LAMP3) Antibody (Biotin)
169€ (20 µg)
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935106861
info@markelab.com
name
Lysosomal Associated Membrane Protein 3 (LAMP3) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx336434
tested applications
ELISA
Description
LAMP3 Antibody (Biotin) is a Rabbit Polyclonal against LAMP3.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Lysosomal Associated Membrane Protein 3 (LAMP3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9UQV4 |
| Gene ID | 27074 |
| Alias | CD208,DC LAMP,DC-LAMP,DCLAMP,LAMP,LAMP-3,TSC403,DC-lysosome-associated membrane glycoprotein |
| Background | Antibody anti-LAMP3 |
| Status | RUO |
Descripción
Lysosome-associated membrane glycoprotein 3 (LAMP3), also known as DC-LAMP, is a lysosomal membrane protein predominantly expressed in dendritic cells and other immune cells, where it plays a critical role in antigen processing and presentation LAMP3 expression increases during dendritic cell maturation, facilitating the regulation of lysosomal function and endosomal trafficking It is also involved in lysosome-mediated autophagy and immune responses by regulating cellular degradation pathways Dysregulation of LAMP3 has been linked to cancer progression and metastasis, particularly in breast, cervical, and lung cancers, where its overexpression promotes tumor cell survival and invasion through altered lysosomal activity Additionally, LAMP3 has been implicated in hypoxia response pathways, contributing to cellular adaptation to low oxygen environments Emerging studies highlight its role in viral infections, where it can affect viral replication and host immune response, making LAMP3 a potential biomarker for immune regulation and cancer prognosis
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Lysosomal Associated Membrane Protein 3 (LAMP3) Antibody
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