Lymphocyte Antigen 96 (LY96) Antibody

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292.5€ (80 µl)

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935106861
info@markelab.com
name
Lymphocyte Antigen 96 (LY96) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx029509
tested applications
ELISA, WB

Description

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

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Product specifications

CategoryPrimary Antibodies
Immunogen TargetLymphocyte Antigen 96 (LY96)
HostRabbit
ReactivityHuman
Recommended DilutionWB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified through a protein A column, followed by peptide affinity purification.
Size 180 µl
Size 2400 µl
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS containing 0.09% sodium azide.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDQ9Y6Y9
BackgroundAntibody anti-LY96
StatusRUO

Descripción

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Binds bacterial lipopolysaccharide(LPS)(PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide(LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria(PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B(PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS(PubMed:10359581).

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Lymphocyte Antigen 96 (LY96) Antibody

This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.

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