Lymphocyte Antigen 96 (LY96) Antibody
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Description
LY96 Antibody is a Rabbit Polyclonal against LY96.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Lymphocyte Antigen 96 (LY96) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 20 µl |
| Size 2 | 50 µl |
| Size 3 | 100 µl |
| Size 4 | 200 µl |
| Size 5 | 1 ml |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y6Y9 |
| Gene ID | 23643 |
| NCBI Accession | NP_001182726.1 |
| OMIM | 605243 |
| Background | Antibody anti-LY96 |
| Status | RUO |
Descripción
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Binds bacterial lipopolysaccharide(LPS)(PubMed:17803912, PubMed:17569869). Cooperates with TLR4 in the innate immune response to bacterial lipopolysaccharide(LPS), and with TLR2 in the response to cell wall components from Gram-positive and Gram-negative bacteria(PubMed:11160242, PubMed:11593030). Enhances TLR4-dependent activation of NF-kappa-B(PubMed:10359581). Cells expressing both LY96 and TLR4, but not TLR4 alone, respond to LPS(PubMed:10359581).
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Lymphocyte Antigen 96 (LY96) Antibody
LY96 Antibody is a Rabbit Polyclonal antibody against LY96. This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
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