Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Antibody (FITC)

169€ (20 µg)
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935106861
info@markelab.com
name
Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx304379
Description
LRRN2 Antibody (FITC) is a Rabbit Polyclonal against LRRN2 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Immunogen: Recombinant human Leucine-rich repeat neuronal protein 2 protein (201-500 AA). |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 488 Excitation/Emission: 499/515 |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75325 |
| Gene ID | 10446 |
| OMIM | 605492 |
| Alias | GAC1,LRRN5,LRANK1,FIGLER7,Leucine-rich repeat neuronal protein 5,Glioma amplified on chromosome 1 protein |
| Background | Antibody anti-LRRN2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
LRRN2 is a neuronal protein that belongs to the leucine-rich repeat (LRR) superfamily, known for its involvement in protein-protein interactions that influence neural development and synaptic regulation. LRRN2 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus. The protein plays a key role in neuronal differentiation, axon guidance, and synaptic plasticity. Structurally, LRRN2 contains extracellular leucine-rich repeat domains that mediate interactions with extracellular matrix components and neural ligands, supporting its role in cell adhesion and signal transduction. Recent studies suggest a potential link between LRRN2 dysfunction and neurodevelopmental disorders, underscoring its importance in maintaining neural circuit integrity and proper brain function.
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