Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Antibody

357.5€ (100 µg)
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935106861
info@markelab.com
name
Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx146189
tested applications
ELISA, IHC
Description
LRRN2 Antibody is a Rabbit Polyclonal against LRRN2.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | ELISA: 1/20000 - 1/80000, IHC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified by antigen affinity column chromatography. |
Size 1 | 100 µg |
Size 2 | 1 mg |
Form | Lyophilized |
Tested Applications | ELISA, IHC |
Buffer | Prior to lyophilization: 1% BSA and 0.02% NaN3. |
Availability | Shipped within 7-15 working days. |
Storage | Store at -20 °C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
NCBI Accession | BC034047 |
Alias | GAC1,LRRN5,LRANK1,FIGLER7,Leucine-rich repeat neuronal protein 5,Glioma amplified on chromosome 1 protein |
Background | Antibody anti-LRRN2 |
Status | RUO |
Note | Concentration: Lyophilized form: Not applicable. After reconstitution: 1 mg/ml. - |
Descripción
LRRN2 is a neuronal protein that belongs to the leucine-rich repeat (LRR) superfamily, known for its involvement in protein-protein interactions that influence neural development and synaptic regulation. LRRN2 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus. The protein plays a key role in neuronal differentiation, axon guidance, and synaptic plasticity. Structurally, LRRN2 contains extracellular leucine-rich repeat domains that mediate interactions with extracellular matrix components and neural ligands, supporting its role in cell adhesion and signal transduction. Recent studies suggest a potential link between LRRN2 dysfunction and neurodevelopmental disorders, underscoring its importance in maintaining neural circuit integrity and proper brain function.
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