Leucine-Rich Repeat Neuronal Protein 2 (LRRN2) Antibody

Background

LRRN2 is a neuronal protein that belongs to the leucine-rich repeat (LRR) superfamily, known for its involvement in protein-protein interactions that influence neural development and synaptic regulation. LRRN2 is highly expressed in the brain, particularly in regions associated with learning and memory, such as the hippocampus. The protein plays a key role in neuronal differentiation, axon guidance, and synaptic plasticity. Structurally, LRRN2 contains extracellular leucine-rich repeat domains that mediate interactions with extracellular matrix components and neural ligands, supporting its role in cell adhesion and signal transduction. Recent studies suggest a potential link between LRRN2 dysfunction and neurodevelopmental disorders, underscoring its importance in maintaining neural circuit integrity and proper brain function.