LRRC19 Antibody (FITC)
169€ (20 µg)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
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name
LRRC19 Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx311192
Descripción del producto
LRRC19 Antibody (FITC) is a Rabbit Polyclonal against LRRC19 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | LRRC19 |
| Availability | Shipped within 5-10 working days. |
| Background | Antibody anti-LRRC19 |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Category | Primary Antibodies |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Dry Ice | No |
| Form | Liquid |
| Gene ID | 64922 |
| Host | Rabbit |
| Immunogen Target | LRRC19 |
| Isotype | IgG |
| Name | LRRC19 Antibody (FITC) |
| Price | 169 |
| Provider | Abbexa |
| Purification | Purified by Protein G. |
| Purity | > 95% |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx311192 |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Status | RUO |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| UniProt ID | Q9H756 |
Descripcion del producto en español
Background en español
LRRC19 is a membrane protein implicated in innate immune signaling where it functions as a pattern recognition receptor (PRR) involved in the detection of microbial components it directly activates downstream pathways such as nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) cascades essential for initiating inflammatory responses LRRC19 is predominantly expressed in dendritic cells and macrophages where it contributes to pathogen recognition and the activation of adaptive immunity by promoting antigen presentation studies suggest LRRC19 plays a critical role in the regulation of pro-inflammatory cytokine production and may act as a mediator in host-pathogen interactions its dysregulation has been associated with chronic inflammatory diseases and autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease ongoing research is exploring its potential as a target for modulating inflammatory responses and its involvement in maintaining immune homeostasis during infections and sterile inflammation
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