Low Sample Volume Mouse Leptin Receptor (LEPR) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Low Sample Volume Mouse Leptin Receptor (LEPR) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx575468
tested applications
ELISA
Description
Mouse Leptin Receptor ELISA Kit is an ELISA Kit against Leptin Receptor.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leptin Receptor (LEPR) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 6.25 ng/ml - 400 ng/ml |
| Sensitivity | 3.75 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P48356 |
| Alias | OBR,OB-R,CD295,LEP-R,LEPRD,HuB219,OB receptor |
| Background | Elisa kits for LEPR |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
The leptin receptor (LEPR) is a cell surface receptor that plays a central role in energy homeostasis, metabolism, and body weight regulation. LEPR is the receptor for leptin, a hormone primarily secreted by adipose (fat) tissue that signals satiety and energy sufficiency to the brain. Leptin and its receptor are fundamental to regulating food intake, body weight, and energy expenditure. When leptin binds to LEPR, it triggers a cascade of intracellular signals that inform the central nervous system about the body's energy reserves, particularly in the hypothalamus, which then influences appetite suppression, metabolism, and other endocrine functions. LEPR is essential in maintaining homeostatic control over body mass, as dysregulation or mutations in the leptin receptor pathway can lead to obesity, diabetes, and metabolic syndrome.
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LEPR plays an important role in the regulation of glucose homeostasis via feeding and adiposity. Alternatively spliced transcript variants encoding different isoforms of LEPR have been described. This antibody can recognize long (LEPRb) and short (LEPRa,c,d) isoforms.
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