Low Sample Volume Mouse Intercellular Adhesion Molecule 1 (ICAM1) ELISA Kit

Este producto es parte de ICAM1 - Intercellular adhesion molecule 1
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624€ (96 tests)

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935106861
info@markelab.com
name
Low Sample Volume Mouse Intercellular Adhesion Molecule 1 (ICAM1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx352473
tested applications
ELISA

Description

Mouse Intercellular Adhesion Molecule 1 (ICAM1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Intercellular Adhesion Molecule 1 (ICAM1) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Intercellular Adhesion Molecule 1

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Intercellular Adhesion Molecule 1 (ICAM1)
Reactivity
Mouse
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.312 ng/ml - 20 ng/ml
Sensitivity
< 0.12 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
BB2,CD54,P3.58,ICAM-1
Background
Elisa kits for ICAM1
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

Intercellular Adhesion Molecule 1 (ICAM-1) is a protein encoded by the ICAM1 gene in humans. It plays a crucial role in the immune response by aiding in the adhesion of leukocytes to the endothelial cells lining blood vessels. ICAM-1. It binds to integrins of type CD11a / CD18, or CD11b / CD18 and is also exploited by rhinovirus as a receptor for entry into respiratory epithelium. ICAM-1 is a transmembrane protein possessing an amino-terminus extracellular domain, a single transmembrane domain, and a carboxy-terminus cytoplasmic domain. The structure of ICAM-1 is characterized by heavy glycosylation, and the protein’s extracellular domain is composed of multiple loops created by disulfide bridges within the protein. ICAM-1 is important for the process of leukocyte extravasation, which is how white blood cells move from the bloodstream to infected or injured tissues. It helps leukocytes stick to endothelial cells, a crucial step in the inflammatory response. ICAM-1 can also trigger intracellular signaling events when it binds to its ligands, influencing cellular processes related to inflammation and immune responses.

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