Low Sample Volume Human Interleukin 10 (IL10) ELISA Kit

Este producto es parte de IL10 - Interleukin 10
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624€ (96 tests)

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935106861
info@markelab.com
name
Low Sample Volume Human Interleukin 10 (IL10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx052227
tested applications
ELISA

Description

Human Interleukin 10 (IL10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human IL10 concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Interleukin 10 (IL10)

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Interleukin 10 (IL10)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
7.8 pg/ml - 500 pg/ml
Sensitivity
< 2.8 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.
Availability
Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P22301
Alias
CSIF,GVHDS,IL-10,IL10A,TGIF,Cytokine synthesis inhibitory factor
Background
Elisa kits for IL10
Status
RUO
Note
Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

IL10 is an anti-inflammatory cytokine produced by macrophages, T regulatory cells, and other immune cells to suppress excessive immune responses and maintain tissue homeostasis IL10 signaling occurs through the IL-10 receptor (IL10R) and activates the JAK/STAT3 pathway, inhibiting the production of pro-inflammatory cytokines such as TNF-α, IL1β, and IL6 It plays a pivotal role in immune tolerance, limiting damage caused by chronic inflammation and infections Dysregulation of IL10 expression is associated with autoimmune diseases, such as Crohn's disease, multiple sclerosis, and psoriasis IL10 also exerts immunosuppressive effects in the tumor microenvironment, facilitating tumor progression and immune evasion due to its inhibitory influence on T cells and antigen-presenting cells IL10-based therapies are being explored for managing inflammatory diseases and promoting immune modulation in cancer and chronic infections

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