Low Sample Volume Human Fibroblast Growth Factor 23 (FGF23) ELISA Kit

Este producto es parte de FGF23 - Fibroblast Growth Factor 23
Low Sample Volume Human Fibroblast Growth Factor 23 (FGF23) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

767€ (96 tests)

Elisa kits for FGF23

proveedor

Abbexa

reference

abx053699

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Fibroblast Growth Factor 23 (FGF23) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Fibroblast Growth Factor 23 (FGF23) concentrations in serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Fibroblast Growth Factor 23 (FGF23)


Background

FGF23 is a phosphaturic hormone primarily secreted by osteocytes and osteoblasts in bone tissue. It regulates phosphate homeostasis and vitamin D metabolism by reducing phosphate reabsorption in the kidneys and suppressing the synthesis of 1,25-dihydroxyvitamin D. FGF23 binds to its receptor in the presence of α-Klotho, promoting phosphate excretion to maintain serum phosphate levels. Elevated FGF23 levels are associated with chronic kidney disease (CKD), where impaired renal function leads to hyperphosphatemia and secondary hyperparathyroidism. Mutations in FGF23 can cause disorders like hypophosphatemic rickets and osteomalacia, characterized by bone mineralization defects. FGF23’s role in phosphate balance and bone health makes it a key target for managing CKD and related mineral metabolism disorders.

Características del producto

category

ELISA Kits


immunogen target

Fibroblast Growth Factor 23 (FGF23)


reactivity

Human


test range

15.6 pg/ml - 1000 pg/ml


sensitivity

< 6.2 pg/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ADHR,FGFN,HYPF,HFTC2,HPDR2,PHPTC,Phosphatonin,Tumor-derived hypophosphatemia-inducing factor


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

FGF23


dry ice

No


NCBI accession

NP_065689.1


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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