Low Sample Volume Guinea pig Tumor Necrosis Factor (TNF) ELISA Kit

Este producto es parte de TNF-Tumor Necrosis Factor (Alpha)
Low Sample Volume Guinea pig Tumor Necrosis Factor (TNF) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

662.5€ (96 tests)

Elisa Kits TNF

proveedor

Abbexa

reference

abx051157

Tested Applications

ELISA

reactivity

Guinea pig

status

RUO

clonality

Descripción

Low Sample Guinea pig Tumor Necrosis Factor (TNF) ELISA Kit is an ELISA kit against Guinea Pig Tumor Necrosis Factor α

Background

Tumor Necrosis Factor (TNF) is a versatile cytokine involvedl in numerous physiological and pathological processes. It holds a critical role in modulating immune responses, inflammation, and apoptosis. While predominantly produced by activated macrophages, TNF can also originate from various cell types like lymphocytes, mast cells, endothelial cells, and fibroblasts. Two well-known forms of TNF are TNF-alpha and TNF-beta, also referred to as lymphotoxin-alpha. TNF-alpha, being extensively studied, exists in both soluble and membrane-bound forms, both capable of initiating biological responses by binding to their respective receptors. TNF signaling operates through two receptors: TNFR1 and TNFR2. TNFR1 is ubiquitously expressed across cell types, whereas TNFR2 is primarily found in endothelial, epithelial, and certain immune cells. TNFR1 signaling typically triggers pro-inflammatory and apoptotic responses, while TNFR2 signaling exhibits anti-inflammatory properties and fosters cell proliferation. In autoimmune disease treatment, suppressing TNFR1 signaling has proved significant, whereas TNFR2 signaling supports wound healing.The primary function of TNF lies in regulating immune cells

Características del producto

category

ELISA Kits

immunogen target

Tumor Necrosis Factor (TNF)

reactivity

Guinea pig

test range

7.8 pg/ml - 500 pg/ml

sensitivity

< 2.7 pg/ml

assay type

Sandwich

assay data

Quantitative

sample type

Serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

size 1

96 tests

size 2

5 × 96 tests

size 3

10 × 96 tests

alias

TNF,DIF,TNF-alpha,TNFA,TNFSF2,Tumour necrosis factor,TNF-α,TNLG1F,Tumor necrosis factor alpha, Cachectin

storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit

or code

TNF

dry ice

No

uniprot id

https://www.uniprot.org/uniprotkb/P51435

gene id

https://www.ncbi.nlm.nih.gov/gene/100135630

note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

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