Low Density LRP Antibody

Este producto es parte de LRP1 - LDL receptor related protein 1
Low Density LRP Antibody

Pida mas información

935106861

info@markelab.com

Precio

676€ (100 µg)

Antibody anti-LRP1

proveedor

Abbexa

reference

abx022345

Tested Applications

WB, IHC, FCM

reactivity

status

RUO

clonality

Monoclonal

Descripción

Low Density LRP Antibody is a Mouse monoclonal antibody for lipoproteins against Low Density LRP.


Background

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) is a multifunctional cell surface receptor with diverse roles in cellular processes, including endocytosis, lipid transport, signal transduction, and the regulation of inflammation. Part of the low-density lipoprotein (LDL) receptor family, LRP1 has high sequence homology with the LDL receptor but a much broader set of ligands, facilitating interactions with various proteins, such as apolipoprotein E (ApoE), tissue plasminogen activator (tPA), and matrix metalloproteinases. LRP1 is highly expressed in the liver, brain, and adipose tissues, where it plays crucial roles in metabolism, neuroprotection, and vascular health. In neurons, LRP1 mediates neuroprotective processes and is implicated in the clearance of amyloid-beta, a key protein in Alzheimer’s disease pathology. In addition to metabolic and neural roles, LRP1 impacts cellular migration and adhesion, contributing to processes related to tissue injury repair, cancer metastasis, and inflammatory diseases. Its function and widespread expression make LRP1 a focal point in therapeutic research for conditions including neurodegenerative diseases, atherosclerosis, and certain cancers.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


immunogen target

Low Density LRP


host

Mouse


isotype

IgG2b


conjugation

Unconjugated


form

Liquid


tested applications

WB, IHC, FCM


purification

Purified from ascites.


recommended dilution

Optimal dilutions/concentrations should be determined by the end user.


buffer

Buffer contains no preservative.


size 1

100 µg


storage

Aliquot and store at -70°C. Avoid repeated freeze/thaw cycles.


or code

LRP1


dry ice

No


availability

Shipped within 10-20 working days.


alias

Prolow-density lipoprotein receptor-related protein 1,Alpha-2-macroglobulin receptor,APR,KPA,LRP,A2MR,CD91; DDH3,APOER,LRP1A,TGFBR5,IGFBP3R,IGFBP-3R,IGFBP3R1,LRP-1,Apolipoprotein E receptor


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