Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b Phospho-Tyr292 (FCGR2B pY292) Antibody

Name: Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b Phospho-Tyr292 (FCGR2B pY292) Antibody
Brand: Abbexa
SKU: abx012455
Price: 43.75 EUR
Availability: OnlineOnly

Este producto es parte de FCGR2B - Fc gamma receptor Iib

Pida mas información

935106861

info@markelab.com

Precio

43.75€ (10 µg)

Antibody anti-FCGR2B

proveedor

Abbexa

reference

abx012455

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Rabbit polyclonal antibody against CD32 protein.

Background

FCGR2B (Fc gamma receptor IIB), also known as CD32B, is a low-affinity receptor for the Fc portion of IgG antibodies, primarily responsible for regulating immune responses by mediating inhibitory signaling. It plays a crucial role in the balance between activation and inhibition of immune cells, preventing excessive inflammation and autoimmunity. Unlike its closely related receptor, FCGR2A, which triggers activating signals, FCGR2B is the only inhibitory receptor within the Fc gamma receptor family. This receptor is predominantly expressed on B cells, dendritic cells, macrophages, and other immune cells. FCGR2B is part of the larger family of Fc gamma receptors (FcγRs), which bind the Fc region of immunoglobulin G (IgG) to mediate immune responses such as phagocytosis, cytokine release, and the clearance of immune complexes. Its inhibitory role is vital in the prevention of autoimmune reactions and the modulation of inflammatory responses.

Características del producto

clonality

Polyclonal

reactivity

Human

immunogen target

Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b Phospho-Tyr292 (FCGR2B pY292)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purification

Purified from rabbit antiserum by affinity chromatography using epitope-specifice phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.

buffer

PBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.

size 1

10 µg

size 2

100 µg

size 3

200 µg

size 4

300 µg

size 5

1 mg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

FCGR2B

dry ice

availability

Shipped within 5-10 working days.

alias

CD32,FCG2,CD32B,FCGR2,IGFR2,FCGR2C,FcGRIIB,FcRII-c,FcgammaRIIb,Low affinity immunoglobulin gamma Fc region receptor II-b,IgG Fc receptor II-b,CDw32,Fc-gamma RII-b

uniprot id

https://www.uniprot.org/uniprotkb/P31994

note

This product is for research use only.

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Fc Fragment of IgG, Low Affinity IIb, Receptor For (CD32) (FCGR2B) Antibody

proveedor

Abbexa

reference

abx006667

Tested Applications

reactivity

Human

status

RUO

clonality

Polyclonal

FCGR2B Antibody is a Rabbit Polyclonal Antibody against FCGR2B.

175€ (20 µl)