Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody
819€ (1 ml)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx173379
tested applications
WB, IHC, IF/ICC
Description
This product is currently in development. The lead time for this product may be several months. Please contact us at
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | ELP,SF1,FTZ1,POF7,SF-1,AD4BP,FTZF1,SPGF8,SRXX4,SRXY3,hSF-1,Steroidogenic factor 1,Fushi tarazu factor homolog 1,Nuclear receptor subfamily 5 group A member 1,Adrenal 4-binding protein |
| Background | Antibody anti-NR5A2 |
| Status | RUO |
Descripción
Nuclear receptor subfamily 5 group A member 2 (NR5A2), also known as liver receptor homolog-1 (LRH-1), is a nuclear receptor involved in regulating the expression of genes responsible for bile acid metabolism, cholesterol homeostasis, and the function of the liver and intestine NR5A2 is expressed in tissues such as the liver, pancreas, and ovaries, where it regulates the synthesis and metabolism of cholesterol and bile acids It also plays an essential role in the differentiation of hepatocytes and the maintenance of liver function, including processes like gluconeogenesis and lipid metabolism NR5A2 is involved in controlling the transcription of genes that influence energy metabolism, steroidogenesis, and inflammatory responses Dysregulation of NR5A2 can lead to metabolic disorders, including dyslipidemia and liver disease, and has also been implicated in some cancers, particularly liver and ovarian cancers The role of NR5A2 in maintaining metabolic homeostasis and regulating bile acid synthesis makes it an important target for therapies aimed at treating metabolic and liver-related diseases
Related Products
anti- NR5A2 antibody
Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene(CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development.
Ver Producto
Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody
NR5A2 Antibody is a Rabbit Polyclonal antibody against NR5A2.
Ver Producto
Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody
Rabbit Polyclonal against the NR5A2 protein.
Ver Producto