Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody

Este producto es parte de NR5A - nuclear receptor subfamily 5 group A member
Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody
819€ (1 ml)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx173379
Tested Applications
WB, IHC, IF/ICC

Description

This product is currently in development. The lead time for this product may be several months. Please contact us at

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: Nuclear Receptor Subfamily 5 Group A Member 2 (NR5A2)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Purification
Purified by Protein A and Protein G affinity chromatography.
Size 1
1 ml
Form
Liquid
Tested Applications
WB, IHC, IF/ICC
Buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
Availability
Please enquire.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ELP,SF1,FTZ1,POF7,SF-1,AD4BP,FTZF1,SPGF8,SRXX4,SRXY3,hSF-1,Steroidogenic factor 1,Fushi tarazu factor homolog 1,Nuclear receptor subfamily 5 group A member 1,Adrenal 4-binding protein
Background
Antibody anti-NR5A2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

Nuclear receptor subfamily 5 group A member 2 (NR5A2), also known as liver receptor homolog-1 (LRH-1), is a nuclear receptor involved in regulating the expression of genes responsible for bile acid metabolism, cholesterol homeostasis, and the function of the liver and intestine NR5A2 is expressed in tissues such as the liver, pancreas, and ovaries, where it regulates the synthesis and metabolism of cholesterol and bile acids It also plays an essential role in the differentiation of hepatocytes and the maintenance of liver function, including processes like gluconeogenesis and lipid metabolism NR5A2 is involved in controlling the transcription of genes that influence energy metabolism, steroidogenesis, and inflammatory responses Dysregulation of NR5A2 can lead to metabolic disorders, including dyslipidemia and liver disease, and has also been implicated in some cancers, particularly liver and ovarian cancers The role of NR5A2 in maintaining metabolic homeostasis and regulating bile acid synthesis makes it an important target for therapies aimed at treating metabolic and liver-related diseases

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