LIM/Homeobox Protein Lhx8 (LHX8) Antibody

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Description
Members of the LIM Homeobox gene family, such as LHX8, encode transcription regulators that share common structural features. They all contain 2 tandemly repeated cysteine-rich double-zinc finger motifs, called LIM domains, in addition to a homeodomain. The homeodomain is a DNA-binding domain, and the LIM domains are essential for regulating the activity of these molecules by interacting with other Proteins. Members of the LIM Homeobox gene family are required for the patterning or the specification and differentiation of different cell types during embryonic development (Zhao et al., 1999 [PubMed 10611327]).
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Product specifications
Category | Primary Antibodies |
Immunogen Target | LIM/Homeobox Protein Lhx8 (LHX8) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified through a protein A column, followed by peptide affinity purification. |
Size 1 | 80 µl |
Size 2 | 400 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | PBS containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q68G74 |
Gene ID | 431707 |
OMIM | 604425 |
Background | Antibody anti-LHX8 |
Status | RUO |
Descripción
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LIM/Homeobox Protein Lhx8 (LHX8) Antibody
LHX8 Antibody is a Rabbit Polyclonal antibody against LHX8. The Protein encoded by this gene is a member of the LIM Homeobox family of Proteins, which are involved in patterning and differentiation of various tissue types. These Proteins contain two tandemly repeated cysteine-rich double-zinc finger motifs known as LIM domains, in addition to a DNA-binding homeodomain. This family member is a transcription factor that plays a role in tooth morphogenesis. It is also involved in oogenesis and in neuronal differentiation. This gene is a candidate gene for cleft palate, and it is also associated with odontoma formation. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].
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