LGR5/GPR49 is an orphan receptor. It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues. Stem cell marker of the intestinal epithelium and the hair follicle. Target gene of Wnt signaling. Expressed in skeletal muscle, placenta, spinal cord, and various region of brain. Expressed at the base of crypts in colonic and small mucosa stem cells. In premalignant cancer expression is not restricted to the cript base. Overexpressed in cancers of the ovary, colon and liver.
Primary Antibodies
Polyclonal
Human, Mouse, Rat
LGR5 (loop2)
Rabbit
Unconjugated
Liquid
ELISA, WB, FCM
Purified Rabbit Polyclonal Antibody.
PBS containing 0.09% sodium azide.
50 µl
200 µl
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
LGR5
No
Shipped within 5-10 working days.
LGR5,GPR49,FEX,GPR67,orphan G protein-coupled receptor HG38,leucine-rich repeat-containing G protein-coupled receptor 5,leucine-rich repeat containing G protein-coupled receptor 5
NP_001264155.1, NP_003658.1
This product is for research use only.
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