Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) Antibody
364€ (100 µg)
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935106861
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name
Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx234778
tested applications
ELISA, WB
Description
LILRB5 Antibody is a Rabbit Polyclonal against LILRB5.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily B Member 5 (LILRB5) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75023 |
| Gene ID | 10990 |
| OMIM | 604814 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 5,LIR8,CD85C,LIR-8,CD85 antigen-like family member C,Leukocyte immunoglobulin-like receptor 8 |
| Background | Antibody anti-LILRB5 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
LILRB5 (Leukocyte Immunoglobulin-Like Receptor B5), also known as ILT7 or CD85c, is part of the LILR (leukocyte immunoglobulin-like receptor) family, which plays a pivotal role in immune regulation. The LILR family includes activating and inhibitory receptors expressed on immune cells, primarily myeloid cells. LILRB5, an inhibitory receptor, is encoded within a highly polymorphic region on chromosome 19q13.4. The inhibitory receptors in this family, including LILRB5, interact with major histocompatibility complex (MHC) molecules and other ligands, modulating imm une responses and promoting tolerance, particularly in tissues prone to autoimmune inflammation or where immune homeostasis is critical. LILRB5 expression is seen in monocytes, macrophages, neutrophils, and dendritic cells. Its function is primarily to transmit inhibitory signals that suppress overactive immune responses, which helps protect tissues from damage during prolonged immune activation or chronic inflammatory diseases
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