Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) Antibody
273€ (100 µl)
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935106861
info@markelab.com
name
Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx104720
tested applications
WB, IHC, IF/ICC
Description
Polyclonal Antibody to Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P97484 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 3,Leukocyte immunoglobulin-like receptor 3,HL9,ILT5,LIR3,PIRB,CD85A,ILT-5,LIR-3,PIR-B,LILRA6,CD85 antigen-like family member A,Immunoglobulin-like transcript 5,Monocyte inhibitory receptor HL9 |
| Background | Antibody anti-LILRB3 |
| Status | RUO |
Descripción
LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3) is a member of the leukocyte immunoglobulin-like receptor (LILR) family, a group of receptors involved in regulating the immune response. LILRB3, also known as CD85A or ILT5 (Immunoglobulin-like Transcript 5), is predominantly expressed on myeloid cells, including monocytes, macrophages, neutrophils, and dendritic cells. These receptors play a crucial role in immune regulation by mediating inhibitory signals that prevent excessive activation of the immune system, contributing to the maintenance of immune homeostasis. LILRB3 belongs to the inhibitory subfamily of LILR receptors, which means it primarily dampens immune responses. It achieves this through the recruitment of tyrosine phosphatases, which inhibit activating signaling pathways, thereby reducing inflammatory responses and promoting immune tolerance. This regulation is important for preventing autoimmune reactions and minimizing tissue damage during inflammatory processes.
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