Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Antibody (PE)
689€ (100 tests)
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Name
Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Antibody (PE)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx270951
Tested Applications
FCM
Description
Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Antibody (PE) is a Rabbit Polyclonal Antibody conjugated to PE against Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) for use in flow cytometry.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Immunogen: Recombinant LILRA3 (Val219-Gly438) expressed in E. coli. |
| Host | Rabbit |
| Reactivity | Human |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/575 |
| Assay Type | Concentration: 0.4 mg/ml |
| Recommended Dilution | FCM: 1 µg (2.5 µl)/106 cells in 100 µl. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | PE |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 10 mM Tris, 150 mM NaCl, pH 8.2, containing 0.02% NaN3, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Leukocyte immunoglobulin-like receptor subfamily A member 3,HM31,HM43,ILT6,LIR4,CD85E,ILT-6,LIR-4,Immunoglobulin-like transcript 6,Leukocyte immunoglobulin-like receptor 4,Monocyte inhibitory receptor HM43/HM31 |
| Background | Antibody anti-LILRA3 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
LILRA3 (Leukocyte Immunoglobulin-Like Receptor A3), also referred to as ILT6 or CD85e, is an intriguing member of the leukocyte immunoglobulin-like receptor (LILR) family, which is predominantly expressed on immune cells. LILRA3 is unique among LILR family members because it lacks a transmembrane domain, functioning as a soluble molecule. Found within the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, LILRA3 plays a significant role in modulating immune responses, particularly in inflammatory pathways. As a soluble receptor, LILRA3 is capable of binding various ligands, which include MHC class I molecules, and thus can modulate signaling pathways related to immune tolerance and immune response activation. Its specific function in the immune system remains somewhat enigmatic, as both pro-inflammatory and inhibitory effects have been suggested. However, it is recognized as a key player in regulating inflammation and immune homeostasis, with particular relevance in autoimmune diseases, infections, and certain cancers
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