Human Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Protein

Name: Human Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) Protein
Brand: Abbexa
SKU: abx067777
Price: 234 EUR
Availability: OnlineOnly

Este producto es parte de LILRA3 - leukocyte immunoglobulin like receptor A3

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein LILRA3

proveedor

Abbexa

reference

abx067777

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Background

LILRA3 (Leukocyte Immunoglobulin-Like Receptor A3), also referred to as ILT6 or CD85e, is an intriguing member of the leukocyte immunoglobulin-like receptor (LILR) family, which is predominantly expressed on immune cells. LILRA3 is unique among LILR family members because it lacks a transmembrane domain, functioning as a soluble molecule. Found within the Leukocyte Receptor Complex (LRC) on chromosome 19q13.4, LILRA3 plays a significant role in modulating immune responses, particularly in inflammatory pathways. As a soluble receptor, LILRA3 is capable of binding various ligands, which include MHC class I molecules, and thus can modulate signaling pathways related to immune tolerance and immune response activation. Its specific function in the immune system remains somewhat enigmatic, as both pro-inflammatory and inhibitory effects have been suggested. However, it is recognized as a key player in regulating inflammation and immune homeostasis, with particular relevance in autoimmune diseases, infections, and certain cancers

Características del producto

origin

Human

host

E. coli

immunogen target

Leukocyte Immunoglobulin Like Receptor Subfamily A, Member 3 (LILRA3)

host

E. coli

conjugation

Unconjugated

form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

500 µg

observerd MW

Molecular Weight: Calculated MW: 27.0 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val219-Gly438 Tag: N-terminal His tag

purity

> 95%

buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

LILRA3

dry ice

availability

Shipped within 5-7 working days.

alias

Leukocyte immunoglobulin-like receptor subfamily A member 3,HM31,HM43,ILT6,LIR4,CD85E,ILT-6,LIR-4,Immunoglobulin-like transcript 6,Leukocyte immunoglobulin-like receptor 4,Monocyte inhibitory receptor HM43/HM31

uniprot id

https://www.uniprot.org/uniprotkb/Q8N6C8

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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Leukocyte Immunoglobulin Like Receptor Subfamily A Member 3 (LILRA3) Antibody

proveedor

Abbexa

reference

abx034800

Tested Applications

ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

May act as soluble receptor for class I MHC antigens.

292.5€ (80 µl)